Detecting anti spike neutralizing igG antibody pre and post covid 19 vaccinations

Abstract

Background: COVID-19 is a world-pandemic that recorded significant mortality. Multiple COVID vaccines have been developed, the earliest of which were Sinopharm and Pfizer vaccines. Aim of study: To compare antibody titers between after vaccination with either one of the 2 vaccines. Methodology: This a cross sectional study in which 119 patients were assessed; 53 patients were vaccinated with Pfizer/BioNTech, 18 with Sinopharm, and 48 unvaccinated. Results: All vaccinated subjects were seroconverted with no significant difference in antibody titers between Pfizer and Sinopharm vaccinees. Conclusion: In conclusion, Both vaccines showed the same efficacy as all the study subjects were seroconverted after the 1st dose of vaccination; however, the present study findings cannot be generalized to the entire population due to the small sample size