Measuring Concentration of Heat Shock Protein Hsp90 and Cysteine Proteinase in Patients with Cryptosporidium and Giardia Lamblia

Abstract

The current study was conducted during 8 months and for the period from the beginning of November 2020 until June 2021, and 212 samples were collected for the auditors to Salah El-Din General Hospital and private laboratories in the city of Tikrit, and for age groups ranging from 1-60 years to investigate the spread of the parasite Giardia lamblia and Cryptosporidium, and the results showed that the infection rate of intestinal parasites was (81.13%), and the percentage of infection with intestinal parasite species was 43.86% for G. lamblia and 37.26% for Cryplosporidium., And the rate of infection with Cryptosporidium was with highest percentage for age groups (40.31) (30-41) years, which amounted to 41.66%, and lowest percentage was in age group (1-10) by (30.5%), The rate of infection with Giardiasis was 43.86%, and the highest percentage of infection was 55.26% in age group (11-20) years, and the lowest percentage was in age group (51-60) years, and it amounted to 33.33., The rate of infection with Giardia increased during January (2021) reaching 51.42%, while percentage decreased during May, reaching 36%, and with Cryptosporidium, the infection increased during May, reaching 48%, and decreased in January 2021, reaching 25.71%. and recorded 34% for females and 59% for males when infected with Giardia, and 40.65% for females and 34.71% for males when infected with Cryptosporidium. , the concentration of heat shock protein HSP90 in serum of those infected with Giardia was (20.5 + 4.8) compared with control group (24.8 +4.96), as well as for the concentration of heat shock protein HSP90 in serum of infected patients with Cryplosporidium was (18.0 + 4.6) compared with control group (24.0 + 4.89), while percentage of cysteine in serum of infected people was (6.07 + 3.45) compared with control group (7.53 + 1.08) as well. As for Cryplosporidium, the incidence of cysteine was (6.55 + 3.36) compared with control group (7.02 + 1.48z