HPLC-Determination of Serum Concentrations of Homocysteine for Women with Recurrent Miscarriage in Diyala Governorate

Abstract

This research determined the amount of homocysteine in the blood serum, by using the High-Performance Liquid Chromatography Technique (HPLC) and the model SYKAMN German[1]. High levels of homocysteine in the serum, are a medical condition called hyperhomocysteinemia. Hyper homocysteinemia produces a significant increase in the chance of miscarriage in early pregnancy loss. The results showed an increase in homocysteine in pregnant women with repeated trimester miscarriage with high homocysteine values. Homocysteine concentrations for three groups, the following values (31.5 µmol / L - 36.5 µmol / L) for women with Recurrent Miscarriage and homocysteine concentrations for pregnancy between the following values (17.5 µ mol / L - 20.6µmol / L) while healthy women were (14.5µmol / L - 11.6 µmol / L.