The Effect of Lipid Polysaccharid on the Tissue Structure of the Intestine of White Mice against Infection with Amoebic Dysentery

Abstract

Amoebic dysentery is aparasitic disease that affects human’s snd its spread is very dangerous. Acompound of LPS extract was used from the wall of gram-negative bacteria in groups of mice. And then it was dosed with the amoebic dysentery as mice were dosed with three concentrations of 0,1 0,2 and 0,3 and the highest effect of the extract was at concentration 0,3 which achieved results of a decrease in the process of villi necrosis in the intestine compared to the control group . the control dosed with parasite the presence of large numbers of parasite in the intestine with goblet cell enlargement with lymphocytes and mucosal degeneration compared with groups treated with LPS extract concentrations 0,1 0,2 and 0,3 mm which showed the presence of little hyperplasia and little infiltration of inflammatory cells with respect to concentration 0,1 and composition normal for intestinal glands, lieberkin crypts and goblet cells at 0,2 concentration and no necrosis with normal composition of enterocytes and goblet cells similer to the negative control group untreated with the parasite .