Risk Factors for Deep Venous Thrombosis in Babylon Governorate, Iraq: a Case Control Study

Abstract

Background: Thrombotic diseases are a major source of morbidity and mortality all around the world. Obesity and metabolic illnesses such as diabetes mellitus are becoming more common. Both of these things are risk factors for the development of DVT.

Objectives: To evaluate the risk factors of DVT of the studied samples in Babylon governorate; to compare between patients with DVT and the control group regarding risk factors of DVT; and to predict variables that contribute to risk factors of DVT among the studied samples.

Patients and Methods: The study was designed as a case-control and has been conducted in the hospital section in the Babylon governorate. The samples were convenient samples (a non-random sampling technique), which included 165 subjects (55 cases and 110 controls). Who agreed to participate and fit the inclusion criteria? Data was collected over a period of four months between the 1st of December 2021 and the 1st of April 2022, and the results were analyzed using univariate and multivariate logistic regression analysis.

Results: The results indicate that patients with an age of over 70 years, female-gender, and smoking duration ≥30 years were significantly related to an increase in risk of DVT (P = 0.046; OR= 8.333; 95% C.I= 1.034-67.142), (P= 0.048; OR= 1.938; 95% C.I= 1.006-3.731), and (P=0.012; OR=18.667; 95%C.I=1.894-184.017) respectively. While participants who had no mechanical injury were likely at a lower risk of DVT than those who had a mechanical injury (P =0.011; OR=0.397; 95%C.I=0.195-0.805). The participants who had immobile sitting positions for <6h/d were likely at a lower risk of DVT (P=0.001; OR=0.329; 95%C.I =0.167-0.650). The results of Multivariate Logistic regression analysis demonstrate that only ‎kidney diseases and varicose thrombosis have a significant association ‎with DVT (OR=3.141, and OR= 3.520) times, respectively.

Conclusion: The study showed that increasing age and chronic diseases such as kidney disease, varicose veins, and rheumatism are significantly associated with an increased risk of obesity.