Correlation Study Between Serum Serotonin Level and Dyspepsia Disorder

Abstract

Dyspepsia is gastrointestinal disorder the commonly causes by alcohol drinking, fast eat, spicy food and other causes, characterized by uncomforted and pain feeling in area of stomach specially in upper portion. Serotonin is hormone derived from tryptophan has role as neurotransmitters in central nerves system actin various regions in human body special in gut, that it act to regulation of motility in gut. This study included selection of 34 individuals classified into group1 (17 individuals) with dyspepsia disorder and group 2 (17 individuals) healthy persons. For both groups measured level of serotonin in serum, then compared between them by T-test statistic method and P-value. Current study explained reduce of serotonin hormone level at group 1 comparison with group 2. Also, this study concluded the SH act as regulation of gastrointestinal functions and any it's reduction at level can cause many gut disorders usually cause dyspepsia disorder.