Effect of cutaneous leishmaniasis on antioxidants and some biochemical parameters of patients with single and multiple ulcers

Abstract

This study examined the comparison between single ulcers and multiple ulcers of the cutaneous leishmaniasis parasite in their effect on some antioxidants. This study included (90) people infected with cutaneous leishmaniasis from Samarra General Hospital in Samarra city in Salah El-Din Governorate for the period from August 2021 to April 2022. (54) a person with multiple ulcers. The results showed a significant decrease (P≤ 0.05) in the activity of catalase in the single ulcer group (U/L 1.1±0.4) and the multi-ulcer group (U/L 0.8±0.2) in comparison with the control group (U/L 1.5±0.8), as well as the Significant differences between single ulcer group (U/L 1.1±0.4) and multiple ulcer group (U/L 0.8±0.2). The results showed a significant decrease (P≤ 0.05) in the activity of glutathione peroxidase in the single ulcer group (pg/ml 15.5±4.4) and the multi-ulcer group (9.5±2.9 pg/ml) in comparison with the control group (pg/ml 21.7±5.3). As well as the significant differences between the group of single ulcers (4.4 ± 15.5 pg/ml) and multiple ulcers (pg/ml 9.5 ± 2.9).