Detection of hyaluronidase (hyase) gene in Propionibacterium acne that isolated in Acne vulgaris patients, Kirkuk-Iraq

Abstract

The study which involved 200 patients with Acne vulgaris, was carried out in Kirkuk City from October 2021 to March 2022. The most common isolated bacteria P.acne 40.5%, followed by S.epidermidis 22.5%, S.aureus 19.5%, and 7% S.pyogenes . The results of our study show that all clinical isolates of P. acnes samples under study have the hyaluronidase gene, and most of them have the ability to degrade hyaluronic acid. The hyaluronidase gene, which was not shown in this study. The high prevalence of this gene in P. acnes isolates makes it interesting as a potential genetic target for the detection of P. acnes samples.