Evaluation of the Level of Interleukin-6 and C-Reactive Protein in Type 2 Diabetic Patients with Candida Sp.

Abstract

Background and objective: Type 2 diabetes is a serious and chronic disease prevalent in the world, so the current study was designed to reveal the role caused by the cumulative high level of glucose in the blood and to study some immunological variables and blood tests in patients with type 2 diabetes. Methods: the study included 57 patients and they were divided into two groups based on the percentage of glycated hemoglobin, the first group included (diabetes typeII patients with have oral candidiasis ,HbA1C ≥7) and the second group included (diabetes typeII with don’t have oral candidiasis ,HbA1C ≥7) while the third group included the healthy group It included 31 individuals, Their ages range between 20-60 years, all patient samples that were taken had a glycated hemoglobin percentage of more than 7. People suffering from chronic diseases such as pressure, heart disease, cancer and immunodeficiency were excluded. Result In type 2 diabetic patients with have Candida and with dont have Candida, elevated IL-6, CRP and elevated WBCs were observed in type 2 diabetic patients with Candida, while LYM was elevated in type 2 diabetic patients without Candida. Conclusion: it was concluded from the study that high blood sugar level and lack of control causes a decrease in the body’s immunity and therefore causes severe inflammatory cases, as well as the appearance of oral candidiasis in abundance as a result of weak immunity.