Investigation Role of Hormones and Lipid Profile in Diabetes Mellitus Type I Patients

Abstract

A study was conducted for 6 months starting from November /2021 to April/2022 in Al-Hassan center for diabetes and endocrinology in Al-Husain medical city of Karbala. The total number of participants are (240) person include (150) patients with type I diabetes mellitus (TΙDM), the males (54) (36 %), the females 96 (64%) and (90) healthy control group, males (36) (40%), females (54) (60%). there was a significant increase in concentrations of each hormone (Leptin, Gharlin, Obestatin and CCK) in patient’s females than males when compared with control. also observed a significant increase in the levels of total CHO, TG, LDL and VLDL and a significant decrease in the levels of HDL in patients when compared with control, the rise in the lipid profile showed in females larger than males. This study clarified a several relationships between the physiological parameters in patients’ group, there were significant positive correlation between age with duration, height, weight and BMI, also found positive correlation between cholesterol and with triglyceride and LDL and positive correlation between TG and VLDL. In addition to, positive correlation between CCK with leptin, Gharlin, Obestatin also there was positive correlation between leptin and both Gharlin, Obestatin.