Application of Different Concentrations of Copper Nanoparticles on Blood Components for Healthy and Patients with Arthritis and Jaundice to Explain Absorption and Fluorescent Spectra in Vitro
Keywords:
CuNPs, Emission and Absorbance spectra, Proteins of plasma and serum.Abstract
Nanotechnology is employed to play a pivotal role in different biological fields, in biomedicine, the Nanoparticles are used to diagnose and treatment of a variety of diseases. The present bee research was designed to explain the effects of different concentrations of CuNPs (10μm, 50μm, 100μm) on absorption and fluorescent spectra of blood components for healthy, arthritis, and jaundice (in vitro). The results which are documented from this work confirm that NPs affect the absorption spectra of blood components in different manners and their effects depend on the quality of blood (type of component) so that plasma and serum recorded a significant increase in absorption spectra of healthy blood. Whereas samples of arthritis patients treated with NPs had lower absorbance spectra also the high concentration CuNPs (100 μm) reveal high peak levels. Sample of jaundice patients (bilirubin), the results explained low levels of absorption in most tested samples. Concerning emission spectra, it had been noted increase emission peak in most treated samples of healthy blood samples. as well as samples of arthritis patients treated with NPs indicated a high-level emission in plasma compared with control, On the other hand, the results of other samples showed low emission spectra in an intestine and excited in visible spectra of light compared to control. Showed high peaks of emitted light treated with CuNPs in high concentration treatments of CuNPs. Whereas all the remaining treated samples recorded a significant lowering in emitted spectra compared to those Nano-treated. from this finding, it can bed concluded that the absorption spectra depend on the content proteins of samples and concentration of NPs also, emitted spectra depend on the quality of samples so that has been that bilirubin decreases emitted spectra when treated with CuNPs.
