Study of Some Biochemical Changes in Some Organs of Pregnant Women

Abstract

Conception is a naturalistic physiological report with biochemical, molecular and hormonal alterations that assists the existence and growth of the embryo. Aim of study was to investigate the concentration of thyroid stimulating hormone (TSH), alkaline phosphatase (ALP), and serum electrolyte sodium (Na), potassium(P) and chloride (Cl) in pregnancy. Materials and methods: 22 healthy pregnant females and11 healthy non pregnant females at the age of 15-49 years. Eleven of pregnant females in the first three month of pregnancy and another eleven in the last three month of pregnancy. Blood was pulled and centrifuged to obtain the serum then the serum place in small tubes and stored in -20Co to use it in measure of TSH, ALP and electrolyte (Na,P, Cl ). Results: The study found that there is anon significant increase in TSH in first trimester and anon significantly reduce in the level of TSH in third trimester when compared with control group and there is a significant low in the level of ALP in the first and third trimester of pregnancy when compared with control collection. The study also found that there is anon significant decrease in Na, P in the first three month and significant increase in the last three month of pregnancy compared with control collection. There is anon significant increase in the concentration of chloride Cl in the first and anon significant decrease in the third trimester when compared with control group. Conclusions: There is an alteration in the concentrations of TSH, ALP, Na, P and Cl.