Synthesis and Characterization of some new Heterocyclic Compounds Prepared from Benzoimidazole Derivatives and Study of the Biological Activity

Abstract

This research Included the preparation and characterization some novel five and seven member Heterocyclic Compounds (imidazolidine,Thiazolidine,oxazepine.) .The first step in clude react 4-chloro-o.phenylene amine with Anthranillic acid to get benz imidazolidined erivative (1). And the step second react (1) with 3-hydroxy benzaldehyde to get schiff base (2). And The three step react P.anisidine with derived (2) to get Azo dye derivative(3), derivative.react (3) with (alanine, glycine,thioglycoliacid, phthalic anhydride ,maleic anhydride)to get imidazoildine (4,5), Thiazolidine (6), oxazepine(7,8 ). Properties of the prepared; These Compounds. Were Identification (FT-IR),('H NMR) and (¹³C-NMR) by spectroscopy thene study their biological effect on two types of bacteria Staphylococcus aureuses (Gram positive) and Escherichia coli (Gram Negative).