Synthesis, Characterization and the Biological Activity of Some new a (Thiadiazolidine and Thiatetrazanonanes Hetrocbiyclic Derivatives from Azine

Abstract

mixture of p-chlorobenzaldehyde with P-hydroxybenzaldehyde, Then was reacted with hydrazine sulphate in the presence of ammonia solution to synthesis Azin derivative (N) , by addition reaction of acetylchloride to azomethene groups and disodiumsulphide tp prepare new derivative of (1,3,4-thiadiazolidine), and bicycle rings (1,3,5,6,8-thiatetrazanonanes). (TLC) technique was used to follow the reaction and after purification of the prepared derivative the melting degrees were measured, the infrared (FTIR-spectra, 1H-NMR-Spectra, 13C-NMR-spectra). Some of these compounds were tested against bacterial activity via E-coli and staphylococcus.