Clinical and Immunological Study of Human Herpes Simplex Virus; CD 56 in Female Suffering from Recurrent Abortion
Keywords:
Recurrent abortion, CD56, uterine natural killer cells, ELISA, HSV2.Abstract
Background: Recurrent abortion (R A) is repeated termination of pre gnancy by elimination of products of conception and embryo with immunologic causes. Natural killer (NK) cells may responsible for immune-modulation in maternal decidua and the trophoblast. Herpes simplex virus 2(HSV-2) is the major sexual transmitted viruses cause of recurrent abortion.
Objective: Investigate the association between CD 56 and theti risk of recurrent abortion among Iraqi women patients.
Materials and Methods: Polymerase chain reaction was performed to detect HSV2 and evaluation of serumCD56 concentration by ELISA kit for all specimen (one hundred-fifty) from healthy and aborted woman
Results: Significant variation detected in distribution frequencies of serum CD56 concentration between case and healthy groups.
Conclusion: As results of current study, CD56 may be considered as a protected factor from recurrent abortion among Iraqi women.
