Association of Parvovirus B19 Infection and increased Some immunological markers among spontaneous abortion Women

Abstract

The purpose of this study was to see if parvovirus (B19) was present in abortion women and if certain cytokines were involved in abortion induction. between August 2021 and January 2022 (2022). A total of 60 women who had previously had abortions were included in the study, as well as 25 healthy pregnant women who showed no evidence of chronic inflammatory disease, were gathered from Al Rifai hospital in Dhi Qar city. The patients range in age from 19 to 50 years. Parvovirus was examined on ELISA in blood samples taken from abortion women and healthy controls. A total of 60 samples were taken, with 17(28.3percent) positive results for parvovirus B19, And 43(71.6%) were negative for parvovirus while pregnant women's samples yielded nil (zero per cent) negative results for every 25 samples, using the ELISA test. The distribution of aborted women according to their abortion frequency was revealed. The first abortion was the highest percentage (34/60). the results appeared as follows at first 8(13.3%), second and third trimesters 7(11.6%) 2(3.3)respectively.Interleukin-2 levels were measured using an ELISA test aborted +parvovirus women show a significant (p=0.0483) were (54.66 ±29.97) compared to pregnant women in the control group (2.312±0.6295).the results revealed there are no significant differences( p=0.1207) in the levels ofC3 (131.0±6.049)in Positive parvovirus B19 were found in when compared to the control group(118.4±5.107). As for the results of complete blood count, they were as follows, lower significant white blood cells levels ( 3.534±0.0776 ) compared to the control group were (7.412±0.4661 ), and lower significant lymphocytes levels(1.128±0.1103) compared to control group were (2.816±0.2416), as well as lower significant haemoglobin (Hb) levels (8.941±0.5584) compared to the control group(11.68±0.1695), on the other hand, the results related to the neutrophil showed that there are no significant differences between the patients and the control group(4.111±0.5345)( 3.224±0.2375)respectively, also PLT, results showed lower significant levels(163.7±22.55) in +Parvovirus aborted women compared to control group(273.6±14.59).