Studying the Incidence and Clinical Significance of Thrombocytopenia in Malaria Patients

Abstract

Background: Hematological abnormalities, including thrombocytopenia, anemia, and leukopenia, are frequently encountered in individuals with malaria. Objective: This study aimed at the assessment of the prevalence of thrombocytopenia in patients diagnosed with malaria in the study population. Study design: A cross-sectional study Place and Duration This study was conducted in Liaquat University of Medical and Health Sciences Jamshoro@Hyderabad from June 2022 to June 2023 Methodology: Patient data, encompassing demographics and medical histories, were collected using a pre-designed proforma. Hematological variables were derived from complete blood count (CBC) results and analyzed with a hematology analyzer. Additionally, clinical examinations were conducted for every participant who tested positive for malaria parasites as examined on a blood smear. The collected data underwent statistical analysis utilizing IBM SPSS version 26. Results: The study included a total of 120 patients, comprising 66 (55%) males and 54 (45%) females. Thrombocytopenia has been seen in 90% (n=108) of the 120 patients suffering from malaria. The breakdown of thrombocytopenia severity revealed grade 1 in 50% (n=60) of patients, grade 2 in 25% (n=30), grade 3 in 15% (n=18), and grade 4 in 10% (n=12) patients. Conclusion: This study affirms a high prevalence of thrombocytopenia among individuals with malaria. The findings underscore the significance of platelet counts as a crucial initial screening parameter for those presenting with acute febrile illnesses.