Association of Microbial Infections with Psychological Stress Patients

Abstract

Background: Stress was associated with certain psychological diseases such as Alzheimer's (AD), Schizophrenia and Major Depression diseases. Objectives: The objective of current study was to Finding the relationship between microbial infections and psychological stress diseases. Materials and methods: 5 ml of blood were collected from patients and apparently healthy control (AHC) groups for viral diagnosis , The stool samples were collected from patients and AHC group for bacterial and parasitical diagnosis. Results: The results of viral diagnosis appeared that HSV-1 test in Alzheimer, Schizophrenia and major depression patients’ groups was (50%), (50%) and (60%) respectively. The results of bacterial diagnosis illustrated that Alzheimer, Schizophrenia and Major depression patients groups in H. pylori was (35%), (25%) and (40%) respectively, E. coli was (55%) (65%) and (70%) respectively, Salmonella ssp. was (20%) (15%) and (20%) respectively, Klebsiella ssp. was (15%) (20%) and (15%) respectively and Proteus ssp. was (30%), (25%) and (25%) respectively. Results of parasitical diagnosis showed that Giardia lamblia in Alzheimer, schizophrenia and major depression patients groups was (35%) (20%) and (25%) respectively, E. histolytica was (15%) (10%) and (20%) respectively and Cryptosporidium parvum was (20%) (10%) and (25%) respectively. Conclusion: From of current study concluded that Microbial infection was associated with psychological stress patients, because the stress leads to minimize the activity and efficiency of immune response against foreign antigens.