Evaluation Some Biochemical Test and Antioxidant in Iraqi Women Patients with Cervical Cancer

Abstract

Background.Reactive oxygen species causes DNA damage and cellular membrane deterioration; Triglycerides have been linked to an increased risk of Cervical cancer (CC). Material and methods: One hundred samples (serum) were taken from patients aged between 20−60 years; Whole blood was allowed to coagulate for one hour at room temperature in order to acquire the serum sample. As well as divided into six groups to achieve the tests which TAC, TC, TG, HDL, LDL, GPX Results: Some important findings were observed regarding the clinical significance from lipid profiles in patients with CC. First, a detailed analysis of the blood lipid differences between patients and healthy women using a relatively large number of CC patients showed that those with the disease had lower levels of HDL cholesterol and higher levels of TC, TG, and LDL cholesterol.Conclusion: In conclusion, a disordered lipid profile with lower HDL levels and greater TG, TC, and LDL levels may be linked to cervical cancer. CC exhibits oxidative stress, which is reflected by altered antioxidative enzyme activity, increased lipid peroxidation, this stress is accentuated in later stages by the increasing tumor burden.